Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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241
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241
Tocris Bioscience™ Dooku 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Reversibly blocks Yoda1 activity; does not affect constitutive Piezo1 activity
| Target | Other Piezo Channel Compounds |
|---|---|
| CAS | 2253744-54-4 |
| Purity | 98% |
| Chemical Name or Material | 2-[(2,6-Dichlorobenzyl)thio)-5-(1 H-pyrrol-2-yl)-1,3,4-oxadiazole |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C13H9Cl2N3OS |
| Formula Weight | 326.2 |
242
Tocris Bioscience™ BTD
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective TRPC5 activator
| CAS | 896684-04-1 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 6-Methyl-N-[3-(tricyclo[3.3.1.13,7]dec-1-yloxy)propyl]-4H-1,2,4-benzothiadiazine-3-propanamide-1,1-dioxide |
| Molecular Formula | C24H33N3O4S |
243
R&D Systems™ Cy5-Fuc Labeled N2nf (Cy5-N2nf)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Used as a ligand for lectins and to study glycan protein interaction
244
Tocris Bioscience™ FSEN 1
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Induces ferroptosis; inhibits FSP1
| Target | Ferroptosis Inhibitors |
|---|---|
| CAS | 862808-01-3 |
| Purity | 0.98 |
| Chemical Name or Material | 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H22BrN5OS |
245
| Shipping Condition | No special requirements |
|---|---|
| CAS | 24868-20-0 |
| Color | Yellow to Orange to Brown |
| Solubility | slightly soluble aq. soln. |
| Purity | ≥97.5% |
| Physical Form | Crystalline Powder |
| Chemical Name or Material | Dantrolene sodium hemiheptahydrate |
| Recommended Storage | Freezer -20°C |
| Synonym | 1-[(5-(p-Nitrophenyl)-furfurylidene)amino]hydantoin sodium salt |
| Molecular Formula | C14 H9 N4 Na O5 · 3.5 H2O |
| Melting Point | 225°C to 226°C |
| Product Line | Life science |
246
Thermo Scientific Chemicals Pictilisib, 95%
CAS: 957054-30-7 Molecular Formula: C23H27N7O3S2 Molecular Weight (g/mol): 513.64 InChI Key: LHNIIDJUOCFXAP-UHFFFAOYSA-N IUPAC Name: 4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-1H-indazole SMILES: CS(=O)(=O)N1CCN(CC2=CC3=NC(=NC(N4CCOCC4)=C3S2)C2=C3C=NNC3=CC=C2)CC1
| CAS | 957054-30-7 |
|---|---|
| Molecular Weight (g/mol) | 513.64 |
| SMILES | CS(=O)(=O)N1CCN(CC2=CC3=NC(=NC(N4CCOCC4)=C3S2)C2=C3C=NNC3=CC=C2)CC1 |
| IUPAC Name | 4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-1H-indazole |
| InChI Key | LHNIIDJUOCFXAP-UHFFFAOYSA-N |
| Molecular Formula | C23H27N7O3S2 |
247
Tocris Bioscience™ AZ 5704
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective ATM kinase inhibitor; orally bioavailable
| CAS | 1941214-06-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C23H23FN6O2 |
| Formula Weight | 434.47 |
249
Tocris Bioscience™ Abiraterone acetate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent CYP17A1 inhibitor
250
| Shipping Condition | No special requirements |
|---|---|
| CAS | 58-46-8 |
| Color | White to Light-yellow to Beige |
| Purity | ≥97.5% |
| Physical Form | Crystalline Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Tetrabenazine |
| Recommended Storage | Refrigerator +4°C |
| Molecular Formula | C19 H27 N O3 |
| EINECS Number | 200-383-6 |
| Melting Point | 124°C to 130°C |
| Product Line | Life science |
251
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Thermo Scientific Chemicals Tolvaptan
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Thermo Scientific Chemicals Tolvaptan
CAS: 150683-30-0 Molecular Formula: C26H25ClN2O3
| CAS | 150683-30-0 |
|---|---|
| Molecular Formula | C26H25ClN2O3 |
252
Tocris Bioscience™ Janelia Fluor 526, SE
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fluorogenic yellow dye; for SMLSM; λabsλem 526/550 nm
253
Tocris Bioscience™ DSPE-PEG 2000 Maleimide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PEGylated DSPE with a maleimide reactive group
254
Tocris Bioscience™ SGC AAK1 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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AAK1 and BMP2K inhibitor; activates Wnt signaling
| CAS | 2247894-32-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(6-(3-((N,N-diethylsulfamoyl)amino)phenyl)-1H-indazol-3-yl)cyclopropanecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H25N5O3S |
| Formula Weight | 427.52 |
255
Thermo Scientific™ Fosinopril (sodium), 98%
CAS: 88889-14-9 Molecular Formula: C30H45NNaO7P Molecular Weight (g/mol): 585.65 MDL Number: MFCD00897699 InChI Key: TVTJZMHAIQQZTL-HREVRLCXSA-M IUPAC Name: sodium (2S,4S)-4-cyclohexyl-1-(2-{[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate SMILES: [Na+].CCC(=O)OC(OP(=O)(CCCCC1=CC=CC=C1)CC(=O)N1C[C@@H](C[C@H]1C([O-])=O)C1CCCCC1)C(C)C
| CAS | 88889-14-9 |
|---|---|
| Molecular Weight (g/mol) | 585.65 |
| MDL Number | MFCD00897699 |
| SMILES | [Na+].CCC(=O)OC(OP(=O)(CCCCC1=CC=CC=C1)CC(=O)N1C[C@@H](C[C@H]1C([O-])=O)C1CCCCC1)C(C)C |
| IUPAC Name | sodium (2S,4S)-4-cyclohexyl-1-(2-{[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate |
| InChI Key | TVTJZMHAIQQZTL-HREVRLCXSA-M |
| Molecular Formula | C30H45NNaO7P |